Indication

Listeria endocarditis

Listeria endocarditis is a rare, life-threatening form of infective endocarditis caused by the foodborne, facultative intracellular Gram-positive bacterium *Listeria monocytogenes*. Read more about Listeria endocarditis

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About Listeria endocarditis.

Listeria endocarditis is a rare, life-threatening form of infective endocarditis caused by the foodborne, facultative intracellular Gram-positive bacterium *Listeria monocytogenes*.

The infection primarily targets the cardiovascular system, with a marked predilection for left-sided heart structures—especially the aortic and mitral valves—and frequently affects older adults, immunocompromised patients, or individuals with prosthetic valves or preexisting structural heart disease.

Pathophysiologically, sustained bacteremia enables bacterial adherence and biofilm formation on native or prosthetic endocardial surfaces, precipitating valvular vegetation, tissue destruction, and regurgitation.

Defining clinical features include persistent fever, new or changing cardiac murmurs, acute or worsening heart failure, and a high incidence of systemic septic embolization.

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