Maintenance of healing duodenal ulcer

Maintenance of healing duodenal ulcer refers to the post-acute management phase in patients who have achieved endoscopic re-epithelialization or complete resolution of an active peptic ulcer located in the proximal small intestine

Maintenance of healing duodenal ulcer refers to the post-acute management phase in patients who have achieved endoscopic re-epithelialization or complete resolution of an active peptic ulcer located in the proximal small intestine

Duodenal ulcers arise from mucosal breakdown in the duodenal bulb when aggressive factors, primarily gastric acid and pepsin, overwhelm endogenous mucosal defense mechanisms, frequently triggered by persistent *Helicobacter pylori* infection or chronic nonsteroidal anti-inflammatory drug use

This clinical state focuses on sustained acid suppression or mucosal cytoprotection to prevent lesion recurrence and subsequent complications, such as gastrointestinal hemorrhage, perforation, or gastric outlet obstruction, particularly in individuals with recurrent ulcer disease, incomplete eradication of risk factors, or continued exposure to ulcerogenic agents

This clinical state focuses on sustained acid suppression or mucosal cytoprotection to prevent lesion recurrence and subsequent complications, such as gastrointestinal hemorrhage, perforation, or gastric outlet obstruction, particularly in individuals with recurrent ulcer disease, incomplete eradication of risk factors, or continued exposure to ulcerogenic agents

This clinical state focuses on sustained acid suppression or mucosal cytoprotection to prevent lesion recurrence and subsequent complications, such as gastrointestinal hemorrhage, perforation, or gastric outlet obstruction, particularly in individuals with recurrent ulcer disease, incomplete eradication of risk factors, or continued exposure to ulcerogenic agents