Maintenance of healing erosive esophagitis

Maintenance of healing of erosive esophagitis refers to an ongoing therapeutic clinical state in patients with gastroesophageal reflux disease who have achieved endoscopic resolution of esophageal mucosal breaks, ulcerations, or erosions following acute acid-suppression therapy Pathophysiologically, the esophageal squamous epithelium remains vulnerable to recurrent injury from chronic retrograde flow of gastric acid, pepsin, and bile acids Without sustained therapy, the majority of patients expe...

Maintenance of healing of erosive esophagitis refers to an ongoing therapeutic clinical state in patients with gastroesophageal reflux disease who have achieved endoscopic resolution of esophageal mucosal breaks, ulcerations, or erosions following acute acid-suppression therapy

Without sustained therapy, the majority of patients experience rapid relapse of mucosal erosion and associated reflux symptoms

This long-term clinical strategy aims to preserve intact mucosal architecture, maintain symptom remission, and prevent progressive complications such as peptic strictures, gastrointestinal bleeding, and Barrett's esophagus