Malignant ascites

Malignant ascites is the abnormal accumulation of protein-rich fluid containing malignant cells within the peritoneal cavity, representing a complication of advanced or recurrent neoplasms It most frequently arises in patients with peritoneal carcinomatosis secondary to ovarian, gastrointestinal, breast, or primary peritoneal malignancies Clinically, affected individuals experience progressive abdominal distension, early satiety, pain, dyspnea, and peripheral edema, typically accompanied by an e...

Malignant ascites is the abnormal accumulation of protein-rich fluid containing malignant cells within the peritoneal cavity, representing a complication of advanced or recurrent neoplasms

It most frequently arises in patients with peritoneal carcinomatosis secondary to ovarian, gastrointestinal, breast, or primary peritoneal malignancies Clinically, affected individuals experience progressive abdominal distension, early satiety, pain, dyspnea, and peripheral edema, typically accompanied by an exudative fluid profile characterized by a low serum-ascites albumin gradient

It most frequently arises in patients with peritoneal carcinomatosis secondary to ovarian, gastrointestinal, breast, or primary peritoneal malignancies

It most frequently arises in patients with peritoneal carcinomatosis secondary to ovarian, gastrointestinal, breast, or primary peritoneal malignancies Pathophysiologically, the condition is driven by tumor-induced neoangiogenesis, cytokine-mediated increase in microvascular permeability—notably involving vascular endothelial growth factor—and impaired lymphatic drainage due to tumor obstruction of subdiaphragmatic lymphatics Clinically, affected individuals experience progressive abdominal dist...

Pathophysiologically, the condition is driven by tumor-induced neoangiogenesis, cytokine-mediated increase in microvascular permeability—notably involving vascular endothelial growth factor—and impaired lymphatic drainage due to tumor obstruction of subdiaphragmatic lymphatics

Clinically, affected individuals experience progressive abdominal distension, early satiety, pain, dyspnea, and peripheral edema, typically accompanied by an exudative fluid profile characterized by a low serum-ascites albumin gradient