Migraine prevention

Migraine prevention refers to prophylactic therapy indicated for individuals with migraine, a chronic neurovascular disorder of the central nervous system characterized by recurrent, moderate-to-severe throbbing headache attacks frequently accompanied by nausea, photophobia, phonophobia, or focal neurological auras

Migraine prevention refers to prophylactic therapy indicated for individuals with migraine, a chronic neurovascular disorder of the central nervous system characterized by recurrent, moderate-to-severe throbbing headache attacks frequently accompanied by nausea, photophobia, phonophobia, or focal neurological auras Prophylaxis is clinically indicated for both episodic and chronic migraine to decrease attack frequency, duration, and severity, particularly in patients experiencing frequent monthly...

Prophylaxis is clinically indicated for both episodic and chronic migraine to decrease attack frequency, duration, and severity, particularly in patients experiencing frequent monthly headache days, profound functional disability, or intolerance or inadequate response to acute abortive therapies

Prophylaxis is clinically indicated for both episodic and chronic migraine to decrease attack frequency, duration, and severity, particularly in patients experiencing frequent monthly headache days, profound functional disability, or intolerance or inadequate response to acute abortive therapies

Pathophysiologically, preventive interventions target trigeminovascular system hyperexcitability, cortical spreading depression, central sensitization, and the release of inflammatory neuropeptides such as calcitonin gene-related peptide to suppress recurrent neurogenic neuroinflammation