Mucocutaneous herpes simplex

Mucocutaneous herpes simplex refers to a localized viral infection of the skin and mucous membranes caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) It primarily affects the integumentary and mucosal epithelial surfaces—most frequently involving the oral, perioral, or anogenital regions—in both immunocompetent and immunocompromised hosts Pathophysiologically, the virus replicates within epithelial cells following primary exposure or reactivation from latent sensory nerve ganglia, ...

Mucocutaneous herpes simplex refers to a localized viral infection of the skin and mucous membranes caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) While typically episodic and self-limited in healthy individuals, the condition can present with prolonged, extensive, or necrotic ulcerations in patients with impaired cell-mediated immunity

It primarily affects the integumentary and mucosal epithelial surfaces—most frequently involving the oral, perioral, or anogenital regions—in both immunocompetent and immunocompromised hosts

Pathophysiologically, the virus replicates within epithelial cells following primary exposure or reactivation from latent sensory nerve ganglia, clinically producing clusters of painful, fluid-filled vesicles on an erythematous base that subsequently rupture, ulcerate, and crust

While typically episodic and self-limited in healthy individuals, the condition can present with prolonged, extensive, or necrotic ulcerations in patients with impaired cell-mediated immunity