Indication

Narcolepsy syndrome

Narcolepsy syndrome is a chronic neurological disorder of central hypersomnolence that impairs the brain's ability to regulate normal sleep-wake cycles. Read more about Narcolepsy syndrome

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Drugs that treat it

Common Narcolepsy syndrome therapies.

Showing 28–36 of 174 drugs

MODAFINIL

NARCOLEPSY SYNDROME·+2
KARALEX PHARMA,

MODAFINIL

AMPHETAMINES/ANOREXIANTS/STIMULANTS·NARCOLEPSY SYNDROME·+2
APOTEX CORP

MODAFINIL

AMPHETAMINES/ANOREXIANTS/STIMULANTS·NARCOLEPSY SYNDROME·+2
INGENUS PHARMAC
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About Narcolepsy syndrome.

Narcolepsy syndrome is a chronic neurological disorder of central hypersomnolence that impairs the brain's ability to regulate normal sleep-wake cycles.

It typically manifests in adolescents and young adults, affecting the central nervous system through disrupted sleep architecture and rapid-onset rapid eye movement (REM) sleep.

Clinically, it is defined by persistent excessive daytime sleepiness and irresistible sleep attacks, frequently accompanied by cataplexy, sleep paralysis, hypnagogic or hypnopompic hallucinations, and fragmented nighttime sleep.

Pathophysiologically, the primary form involves an autoimmune-mediated loss of orexin- (hypocretin-) producing neurons in the lateral hypothalamus, leading to severe deficiency of this wake-promoting neuropeptide.

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