Neuroblastoma

Neuroblastoma is a malignant embryonal malignancy of the peripheral sympathetic nervous system that arises from immature nerve cells known as neuroblasts It primarily affects infants and young children, most commonly occurring under five years of age The disease most frequently originates in the adrenal medulla or along the paraspinal sympathetic chain in the abdomen, chest, neck, or pelvis

Neuroblastoma is a malignant embryonal malignancy of the peripheral sympathetic nervous system that arises from immature nerve cells known as neuroblasts

It primarily affects infants and young children, most commonly occurring under five years of age The disease most frequently originates in the adrenal medulla or along the paraspinal sympathetic chain in the abdomen, chest, neck, or pelvis

Clinically, neuroblastoma exhibits extreme biological heterogeneity, ranging from asymptomatic localized tumors that may spontaneously regress to aggressive, widely metastatic disease commonly involving the bone marrow, skeleton, liver, and distant lymph nodes

Clinically, neuroblastoma exhibits extreme biological heterogeneity, ranging from asymptomatic localized tumors that may spontaneously regress to aggressive, widely metastatic disease commonly involving the bone marrow, skeleton, liver, and distant lymph nodes