Indication

Neurogenic detrusor overactivity

Neurogenic detrusor overactivity is a form of neurogenic lower urinary tract dysfunction characterized by involuntary contractions of the detrusor smooth muscle during the bladder filling phase. Read more about Neurogenic detrusor overactivity

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About Neurogenic detrusor overactivity.

Neurogenic detrusor overactivity is a form of neurogenic lower urinary tract dysfunction characterized by involuntary contractions of the detrusor smooth muscle during the bladder filling phase.

This condition affects the genitourinary system in individuals with underlying central nervous system diseases or injuries, most commonly suprasacral spinal cord injury, multiple sclerosis, spina bifida, or stroke.

Clinically, it manifests as urinary urgency, frequency, and urge incontinence, which may occur with or without sensation depending on the neurological lesion.

Pathophysiologically, the loss of higher inhibitory neural control causes detrusor hyperreflexia and elevated intravesical storage pressures, creating a significant risk for vesicoureteral reflux, hydronephrosis, and long-term renal damage.

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