Neurosyphilis

Neurosyphilis is an infection of the central nervous system caused by the spirochete bacterium *Treponema pallidum* It can occur at any stage of syphilis following early hematogenous dissemination and invasion of the cerebrospinal fluid, meninges, cerebral vasculature, or brain and spinal cord parenchyma

It can occur at any stage of syphilis following early hematogenous dissemination and invasion of the cerebrospinal fluid, meninges, cerebral vasculature, or brain and spinal cord parenchyma Pathophysiologically and clinically, it encompasses early forms characterized by asymptomatic involvement, acute syphilitic meningitis, cranial nerve palsies, or meningovascular endarteritis leading to stroke, as well as late parenchymal manifestations that typically develop years to decades later, such as ge...

It can occur at any stage of syphilis following early hematogenous dissemination and invasion of the cerebrospinal fluid, meninges, cerebral vasculature, or brain and spinal cord parenchyma Pathophysiologically and clinically, it encompasses early forms characterized by asymptomatic involvement, acute syphilitic meningitis, cranial nerve palsies, or meningovascular endarteritis leading to stroke, as well as late parenchymal manifestations that typically develop years to decades later, such as ge...