Indication

Pasteurella multocida endocarditis

*Pasteurella multocida* endocarditis is an uncommon, severe zoonotic infection of the cardiovascular system characterized by colonization and inflammation of the endocardial surface, primarily affecting native or prosthetic heart valves. Read more about Pasteurella multocida endocarditis

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About Pasteurella multocida endocarditis.

*Pasteurella multocida* endocarditis is an uncommon, severe zoonotic infection of the cardiovascular system characterized by colonization and inflammation of the endocardial surface, primarily affecting native or prosthetic heart valves.

It typically arises after exposure to domestic animals, such as dogs or cats, through bites, scratches, or contact with mucosal secretions that introduce the Gram-negative coccobacillus into the bloodstream.

The condition disproportionately affects immunocompromised individuals, older adults, and patients with pre-existing valvular disease or chronic liver cirrhosis.

Pathophysiologically, sustained bacteremia promotes bacterial adherence and the formation of destructive vegetations on cardiac valves, frequently manifesting with persistent bacteremia, heart murmurs, progressive valvular dysfunction, and systemic embolic complications.

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