Indication

Penile carcinoma

Penile carcinoma is a rare malignancy of the male external genitalia, originating within the epithelial tissues of the penis. Read more about Penile carcinoma

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About Penile carcinoma.

Penile carcinoma is a rare malignancy of the male external genitalia, originating within the epithelial tissues of the penis.

The vast majority of cases are squamous cell carcinomas arising from the mucosal lining of the glans penis or the inner prepuce.

Clinically, it typically manifests as a painless exophytic mass, nonhealing ulcer, erythematous patch, or verrucous plaque, often associated with risk factors such as high-risk human papillomavirus (HPV) infection, phimosis, chronic local inflammation, and tobacco use.

Pathophysiologically, the tumor can invade underlying penile structures, including the dartos fascia, corpus spongiosum, and corpora cavernosa, with an established propensity for early locoregional dissemination to inguinal and pelvic lymph nodes.

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