Perennial allergic rhinitis

Perennial allergic rhinitis is a chronic, non-seasonal inflammatory disorder of the nasal mucosa triggered by continuous or year-round exposure to indoor aeroallergens, such as house dust mites, animal dander, mold spores, and cockroach antigens Pathophysiologically, the condition is driven by an immunoglobulin E (IgE)–mediated type I hypersensitivity reaction, leading to mast cell and basophil activation followed by eosinophilic infiltration and cytokine release

Perennial allergic rhinitis is a chronic, non-seasonal inflammatory disorder of the nasal mucosa triggered by continuous or year-round exposure to indoor aeroallergens, such as house dust mites, animal dander, mold spores, and cockroach antigens It affects both pediatric and adult populations, frequently coexisting with other atopic conditions like asthma and atopic dermatitis

It affects both pediatric and adult populations, frequently coexisting with other atopic conditions like asthma and atopic dermatitis Clinically, it is characterized by persistent nasal congestion, rhinorrhea, nasal pruritus, postnasal drip, and sneezing occurring for an hour or more on most days throughout the year

Pathophysiologically, the condition is driven by an immunoglobulin E (IgE)–mediated type I hypersensitivity reaction, leading to mast cell and basophil activation followed by eosinophilic infiltration and cytokine release

Clinically, it is characterized by persistent nasal congestion, rhinorrhea, nasal pruritus, postnasal drip, and sneezing occurring for an hour or more on most days throughout the year