Plague

Plague is an acute, severe zoonotic infection caused by the Gram-negative coccobacillus *Yersinia pestis*, primarily transmitted to humans via the bites of infected rodent fleas, direct contact with infectious animal tissues, or inhalation of respiratory droplets

Plague is an acute, severe zoonotic infection caused by the Gram-negative coccobacillus *Yersinia pestis*, primarily transmitted to humans via the bites of infected rodent fleas, direct contact with infectious animal tissues, or inhalation of respiratory droplets It affects multiple organ systems, most notably the lymphatic, vascular, and respiratory systems across pediatric and adult populations Pathophysiologically, the organism proliferates within the host and circumvents immune defenses, pre...

Plague is an acute, severe zoonotic infection caused by the Gram-negative coccobacillus *Yersinia pestis*, primarily transmitted to humans via the bites of infected rodent fleas, direct contact with infectious animal tissues, or inhalation of respiratory droplets Pathophysiologically, the organism proliferates within the host and circumvents immune defenses, presenting clinically as painful regional lymphadenitis known as bubonic plague, primary or secondary septicemic plague marked by bacteremi...

It affects multiple organ systems, most notably the lymphatic, vascular, and respiratory systems across pediatric and adult populations Pathophysiologically, the organism proliferates within the host and circumvents immune defenses, presenting clinically as painful regional lymphadenitis known as bubonic plague, primary or secondary septicemic plague marked by bacteremia and endotoxemia, or fulminant pneumonic plague