Plasmodium malariae malaria

Plasmodium malariae malaria is a parasitic infection of the red blood cells caused by the protozoan *Plasmodium malariae*, typically transmitted through the bite of an infected female *Anopheles* mosquito The disease primarily affects the hematologic, reticuloendothelial, and renal systems in exposed or resident populations within endemic tropical and subtropical regions

The disease primarily affects the hematologic, reticuloendothelial, and renal systems in exposed or resident populations within endemic tropical and subtropical regions Pathophysiologically, the parasite preferentially infects older erythrocytes and completes a 72-hour asexual erythrocytic schizogony cycle, characteristically producing periodic "quartan" fever paroxysms alongside chills, headache, fatigue, splenomegaly, and anemia

Pathophysiologically, the parasite preferentially infects older erythrocytes and completes a 72-hour asexual erythrocytic schizogony cycle, characteristically producing periodic "quartan" fever paroxysms alongside chills, headache, fatigue, splenomegaly, and anemia