Indication

Primary adrenocortical insufficiency

Primary adrenocortical insufficiency is an endocrine disorder characterized by structural destruction or dysfunction of the adrenal cortex, preventing adequate endogenous production of glucocorticoids and mineralocorticoids. Read more about Primary adrenocortical insufficiency

214 drugs 115 manufacturers

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Drugs that treat it

Common Primary adrenocortical insufficiency therapies.

Showing 145–153 of 214 drugs

PREDNISONE

GLUCOCORTICOSTEROIDS·PULMONARY TUBERCULOSIS·+67
AHP

PREDNISONE

GLUCOCORTICOSTEROIDS·PULMONARY TUBERCULOSIS·+67
PROFICIENT RX L

PREDNISONE

GLUCOCORTICOSTEROIDS·PULMONARY TUBERCULOSIS·+67
BRYANT RANCH PR

PREDNISONE

GLUCOCORTICOSTEROIDS·PULMONARY TUBERCULOSIS·+67
STRIDES PHARMA
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About Primary adrenocortical insufficiency.

Primary adrenocortical insufficiency is an endocrine disorder characterized by structural destruction or dysfunction of the adrenal cortex, preventing adequate endogenous production of glucocorticoids and mineralocorticoids.

Most commonly caused by autoimmune adrenalitis (Addison disease), infections, or genetic conditions, it can affect individuals of any age or sex.

Pathophysiologically, the resulting deficit in cortisol and aldosterone leads to compensatory elevations in adrenocorticotropic hormone (ACTH) and plasma renin activity.

Defining clinical features include chronic fatigue, anorexia, weight loss, orthostatic hypotension, cutaneous hyperpigmentation, hyponatremia, and hyperkalemia, with the potential to progress to life-threatening acute adrenal crisis.

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