Proteus meningitis

Proteus meningitis is a severe, uncommon bacterial infection of the central nervous system characterized by inflammation of the meninges and spinal cord due to species of the gram-negative bacillary genus *Proteus*, most frequently *Proteus mirabilis* The condition predominantly affects neonates and infants through hematogenous seeding, though it can also occur in adults with risk factors such as prior neurosurgical intervention, cranial trauma, structural urinary tract disease, or immunocomprom...

Proteus meningitis is a severe, uncommon bacterial infection of the central nervous system characterized by inflammation of the meninges and spinal cord due to species of the gram-negative bacillary genus *Proteus*, most frequently *Proteus mirabilis* The condition predominantly affects neonates and infants through hematogenous seeding, though it can also occur in adults with risk factors such as prior neurosurgical intervention, cranial trauma, structural urinary tract disease, or immunocomprom...

The condition predominantly affects neonates and infants through hematogenous seeding, though it can also occur in adults with risk factors such as prior neurosurgical intervention, cranial trauma, structural urinary tract disease, or immunocompromising conditions It is clinically distinguished by an aggressive acute course with high rates of intracranial complications, including cerebral abscess formation, ventriculitis, hydrocephalus, and lasting neurological deficits

Pathophysiologically, it produces purulent cerebrospinal fluid pleocytosis, microvascular thrombosis, and severe tissue necrosis It is clinically distinguished by an aggressive acute course with high rates of intracranial complications, including cerebral abscess formation, ventriculitis, hydrocephalus, and lasting neurological deficits

It is clinically distinguished by an aggressive acute course with high rates of intracranial complications, including cerebral abscess formation, ventriculitis, hydrocephalus, and lasting neurological deficits