Pseudomonas aeruginosa biliary tract infection

A Pseudomonas aeruginosa biliary tract infection is a localized or ascending bacterial infection of the hepatobiliary system—most commonly presenting as acute cholangitis or cholecystitis—caused by the opportunistic Gram-negative pathogen *Pseudomonas aeruginosa* It predominantly affects hospitalized, immunocompromised, or surgically altered patients, particularly those with indwelling biliary stents, recent endoscopic retrograde cholangiopancreatography, or malignant and benign biliary duct obs...

A Pseudomonas aeruginosa biliary tract infection is a localized or ascending bacterial infection of the hepatobiliary system—most commonly presenting as acute cholangitis or cholecystitis—caused by the opportunistic Gram-negative pathogen *Pseudomonas aeruginosa* It predominantly affects hospitalized, immunocompromised, or surgically altered patients, particularly those with indwelling biliary stents, recent endoscopic retrograde cholangiopancreatography, or malignant and benign biliary duct obs...

It predominantly affects hospitalized, immunocompromised, or surgically altered patients, particularly those with indwelling biliary stents, recent endoscopic retrograde cholangiopancreatography, or malignant and benign biliary duct obstructions

Pathophysiologically, the organism colonizes and proliferates within static, obstructed bile, often producing biofilms that adhere to ductile epithelium or prosthetic hardware

Clinically, it is characterized by fever, right upper quadrant abdominal pain, and jaundice, with an elevated risk of rapid progression to bacteremia, hepatic abscesses, and life-threatening septic shock due to the pathogen's virulence and frequent multidrug resistance

Clinically, it is characterized by fever, right upper quadrant abdominal pain, and jaundice, with an elevated risk of rapid progression to bacteremia, hepatic abscesses, and life-threatening septic shock due to the pathogen's virulence and frequent multidrug resistance