Indication

Rat-bite fever

Rat-bite fever is a rare zoonotic systemic bacterial infection primarily transmitted to humans through bites, scratches, or contact with mucosal secretions or urine from infected rodents. Read more about Rat-bite fever

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About Rat-bite fever.

Rat-bite fever is a rare zoonotic systemic bacterial infection primarily transmitted to humans through bites, scratches, or contact with mucosal secretions or urine from infected rodents.

The disease is caused by either *Streptobacillus moniliformis*, the predominant pathogen in North America, or *Spirillum minus*, which is more frequently identified in Asia.

Clinically, it is characterized by acute or relapsing fevers, chills, headaches, migratory polyarthralgias, and a maculopapular or petechial rash typically involving the extremities, including the palms and soles.

If left untreated, the bacteremia can disseminate to multiple organ systems, leading to severe complications such as infective endocarditis, septic arthritis, pericarditis, and systemic abscesses.

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