Relapsing polychondritis

Relapsing polychondritis is a rare, systemic autoimmune disease characterized by recurrent, progressive inflammation and destruction of cartilaginous structures and proteoglycan-rich tissues throughout the body It most frequently develops in adults between the fourth and sixth decades of life, presenting with hallmark episodic inflammation of the external ears (auricular chondritis typically sparing the noncartilaginous lobule), nasal cartilage resulting in saddle nose deformity, and peripheral ...

Relapsing polychondritis is a rare, systemic autoimmune disease characterized by recurrent, progressive inflammation and destruction of cartilaginous structures and proteoglycan-rich tissues throughout the body Pathophysiologically driven by an immune-mediated degradation of cartilage matrix proteins, the condition can also cause life-threatening complications, including tracheobronchial collapse, sensorineural hearing loss, ocular inflammation, and cardiovascular involvement

Relapsing polychondritis is a rare, systemic autoimmune disease characterized by recurrent, progressive inflammation and destruction of cartilaginous structures and proteoglycan-rich tissues throughout the body

It most frequently develops in adults between the fourth and sixth decades of life, presenting with hallmark episodic inflammation of the external ears (auricular chondritis typically sparing the noncartilaginous lobule), nasal cartilage resulting in saddle nose deformity, and peripheral joints

It most frequently develops in adults between the fourth and sixth decades of life, presenting with hallmark episodic inflammation of the external ears (auricular chondritis typically sparing the noncartilaginous lobule), nasal cartilage resulting in saddle nose deformity, and peripheral joints