Indication

Seizure occurring during neurosurgery

A seizure occurring during neurosurgery is an acute, paroxysmal neurological complication characterized by abnormal, excessive, and synchronous electrical discharges of cerebral cortical neurons during a cranial operative procedure. Read more about Seizure occurring during neurosurgery

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Common Seizure occurring during neurosurgery therapies.

Showing 28–36 of 72 drugs

PHENYTOIN

TONIC-CLONIC EPILEPSY·+4
ACTAVIS PHARMA,

PHENYTOIN

ANTICONVULSANTS·TONIC-CLONIC EPILEPSY·+4
TARO PHARM USA
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About Seizure occurring during neurosurgery.

A seizure occurring during neurosurgery is an acute, paroxysmal neurological complication characterized by abnormal, excessive, and synchronous electrical discharges of cerebral cortical neurons during a cranial operative procedure.

This condition primarily affects the central nervous system in neurosurgical patients, occurring under general anesthesia or during awake craniotomy with functional cortical mapping.

Pathophysiologically, it is triggered by direct mechanical manipulation, cortical electrical stimulation, acute cerebral ischemia, regional hypoxia, or abrupt shifts in intracranial pressure and local neurochemical homeostasis.

Clinically, these events manifest either as overt motor activity, such as focal or generalized tonic-clonic convulsions, or as subclinical electrographic discharges accompanied by acute physiological instability, including sudden arterial hypertension, tachycardia, increased brain swelling, or elevated end-tidal carbon dioxide.

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