Indication

Severe hypotension

Severe hypotension is an acute, critical cardiovascular state defined by a profound reduction in systemic arterial blood pressure—typically characterized by a systolic blood pressure below 90 mm Hg or a mean arterial pressure below 65 mm Hg—that severely compromises organ perfusion. Read more about Severe hypotension

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About Severe hypotension.

Severe hypotension is an acute, critical cardiovascular state defined by a profound reduction in systemic arterial blood pressure—typically characterized by a systolic blood pressure below 90 mm Hg or a mean arterial pressure below 65 mm Hg—that severely compromises organ perfusion.

It impacts systemic circulation across diverse patient populations, frequently arising from critical etiologies such as distributive, cardiogenic, or hypovolemic shock, sepsis, major trauma, or profound neurogenic failure.

Pathophysiologically, it results from severe depletion of effective circulating volume, diminished cardiac output, or marked loss of systemic vascular resistance, precipitating inadequate cellular oxygen delivery, widespread tissue hypoxia, lactic acidosis, and imminent multisystem organ failure if uncorrected.

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