Squamous cell carcinoma of head and neck

Squamous cell carcinoma of the head and neck is a malignant neoplasm arising from the mucosal epithelium of the upper aerodigestive tract, including the oral cavity, pharynx, larynx, paranasal sinuses, and nasal cavity

Squamous cell carcinoma of the head and neck is a malignant neoplasm arising from the mucosal epithelium of the upper aerodigestive tract, including the oral cavity, pharynx, larynx, paranasal sinuses, and nasal cavity Pathophysiologically, it is characterized by the progressive dysplastic transformation of squamous epithelial cells driven predominantly by chronic exposure to tobacco and alcohol or, particularly in the oropharynx, high-risk human papillomavirus infection

Squamous cell carcinoma of the head and neck is a malignant neoplasm arising from the mucosal epithelium of the upper aerodigestive tract, including the oral cavity, pharynx, larynx, paranasal sinuses, and nasal cavity

Patients commonly present with non-healing mucosal ulcerations, persistent dysphagia, odynophagia, hoarseness, or cervical lymphadenopathy, reflecting high rates of locoregional tissue invasion and regional nodal metastasis

Patients commonly present with non-healing mucosal ulcerations, persistent dysphagia, odynophagia, hoarseness, or cervical lymphadenopathy, reflecting high rates of locoregional tissue invasion and regional nodal metastasis