Staphylococcal meningitis

Staphylococcal meningitis is an acute, severe bacterial infection of the central nervous system characterized by purulent inflammation of the leptomeninges and subarachnoid space caused by species of the genus *Staphylococcus*, most commonly *Staphylococcus aureus* or coagulase-negative staphylococci such as *Staphylococcus epidermidis* It primarily affects neurosurgical patients, individuals with indwelling central nervous system devices—such as cerebrospinal fluid shunts or external ventricula...

It primarily affects neurosurgical patients, individuals with indwelling central nervous system devices—such as cerebrospinal fluid shunts or external ventricular drains—and patients experiencing hematogenous seeding secondary to staphylococcal bacteremia or endocarditis

Clinically, the disease manifests with hallmark features of meningeal irritation, including fever, headache, altered mental status, and nuchal rigidity, accompanied by neutrophilic cerebrospinal fluid pleocytosis, elevated protein levels, and markedly reduced glucose

Clinically, the disease manifests with hallmark features of meningeal irritation, including fever, headache, altered mental status, and nuchal rigidity, accompanied by neutrophilic cerebrospinal fluid pleocytosis, elevated protein levels, and markedly reduced glucose