Staphylococcal prosthetic heart valve endocarditis

Staphylococcal prosthetic heart valve endocarditis is a severe, life-threatening infection of mechanical or bioprosthetic cardiac valves caused by staphylococcal species, predominantly *Staphylococcus aureus* or coagulase-negative staphylococci such as *Staphylococcus epidermidis* Pathophysiologically, the bacteria adhere to the prosthetic material or damaged peri-annular tissue, forming adherent biofilms and destructive vegetations that frequently lead to invasive intracardiac complications, in...

Staphylococcal prosthetic heart valve endocarditis is a severe, life-threatening infection of mechanical or bioprosthetic cardiac valves caused by staphylococcal species, predominantly *Staphylococcus aureus* or coagulase-negative staphylococci such as *Staphylococcus epidermidis*

Staphylococcal prosthetic heart valve endocarditis is a severe, life-threatening infection of mechanical or bioprosthetic cardiac valves caused by staphylococcal species, predominantly *Staphylococcus aureus* or coagulase-negative staphylococci such as *Staphylococcus epidermidis* Clinically, it typically presents with persistent bacteremia, fever, new or changing murmurs, and acute heart failure, accompanied by a high propensity for systemic septic embolization

The disease affects the cardiovascular system of individuals who have undergone surgical or transcatheter valve replacement

Pathophysiologically, the bacteria adhere to the prosthetic material or damaged peri-annular tissue, forming adherent biofilms and destructive vegetations that frequently lead to invasive intracardiac complications, including perivalvular abscesses, valve dehiscence, and severe regurgitation

Pathophysiologically, the bacteria adhere to the prosthetic material or damaged peri-annular tissue, forming adherent biofilms and destructive vegetations that frequently lead to invasive intracardiac complications, including perivalvular abscesses, valve dehiscence, and severe regurgitation