Suppression of recurrent herpes simplex infection

Suppression of recurrent herpes simplex infection refers to long-term, continuous antiviral management aimed at preventing or reducing the frequency and severity of repeated clinical outbreaks and asymptomatic viral shedding caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) Pathophysiologically, the virus establishes life-long latency within sensory nerve ganglia following a primary episode, intermittently reactivating and traveling anterograde along peripheral nerves to the epithe...

Suppression of recurrent herpes simplex infection refers to long-term, continuous antiviral management aimed at preventing or reducing the frequency and severity of repeated clinical outbreaks and asymptomatic viral shedding caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) This clinical state affects mucocutaneous tissues—most commonly the genital tract or orofacial regions—in both immunocompetent individuals with frequent, distressing episodes and immunocompromised populations at...

This clinical state affects mucocutaneous tissues—most commonly the genital tract or orofacial regions—in both immunocompetent individuals with frequent, distressing episodes and immunocompromised populations at risk for prolonged or severe ulcerations Pathophysiologically, the virus establishes life-long latency within sensory nerve ganglia following a primary episode, intermittently reactivating and traveling anterograde along peripheral nerves to the epithelium to cause painful vesicular and ...