Symptomatic congenital syphilis

Symptomatic congenital syphilis is an active, multisystem infectious disease in neonates and infants resulting from transplacental transmission of the spirochete *Treponema pallidum* from an untreated or inadequately treated mother

Symptomatic congenital syphilis is an active, multisystem infectious disease in neonates and infants resulting from transplacental transmission of the spirochete *Treponema pallidum* from an untreated or inadequately treated mother It affects multiple organ systems, most notably the reticuloendothelial, dermatologic, skeletal, hematologic, and central nervous systems It is further characterized pathologically by osseous inflammation, such as osteochondritis and periostitis causing pseudoparalysi...

It affects multiple organ systems, most notably the reticuloendothelial, dermatologic, skeletal, hematologic, and central nervous systems Defining clinical features in early presentation include copious mucopurulent or bloody nasal discharge, maculopapular or vesicular desquamating skin rashes, hepatosplenomegaly, and cholestatic jaundice It is further characterized pathologically by osseous inflammation, such as osteochondritis and periostitis causing pseudoparalysis, alongside nonimmune hydrop...

It affects multiple organ systems, most notably the reticuloendothelial, dermatologic, skeletal, hematologic, and central nervous systems Defining clinical features in early presentation include copious mucopurulent or bloody nasal discharge, maculopapular or vesicular desquamating skin rashes, hepatosplenomegaly, and cholestatic jaundice It is further characterized pathologically by osseous inflammation, such as osteochondritis and periostitis causing pseudoparalysis, alongside nonimmune hydrop...