Treatment to slow progression of coronary artery disease

Coronary artery disease is a chronic cardiovascular disorder characterized by the gradual accumulation of fibrofatty atherosclerotic plaques within the epicardial coronary arteries This process involves lipid retention, chronic vascular inflammation, endothelial dysfunction, and smooth muscle cell proliferation, which progressively narrow the arterial lumen and restrict myocardial perfusion Treatment to slow progression of coronary artery disease targets this underlying vascular pathology in aff...

Coronary artery disease is a chronic cardiovascular disorder characterized by the gradual accumulation of fibrofatty atherosclerotic plaques within the epicardial coronary arteries Clinically, continuing plaque advancement increases the likelihood of luminal stenosis and plaque instability, which may manifest as chronic stable angina, acute coronary syndromes, ischemic cardiomyopathy, or fatal ischemic events

Clinically, continuing plaque advancement increases the likelihood of luminal stenosis and plaque instability, which may manifest as chronic stable angina, acute coronary syndromes, ischemic cardiomyopathy, or fatal ischemic events Treatment to slow progression of coronary artery disease targets this underlying vascular pathology in affected individuals to inhibit further atheroma growth, stabilize vulnerable plaque architecture, and mitigate long-term adverse ischemic complications