Indication

Weight loss due to HIV

Weight loss due to HIV refers to the involuntary, clinically significant depletion of total body mass in individuals infected with the human immunodeficiency virus, often manifesting as HIV-associated wasting syndrome. Read more about Weight loss due to HIV

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About Weight loss due to HIV.

Weight loss due to HIV refers to the involuntary, clinically significant depletion of total body mass in individuals infected with the human immunodeficiency virus, often manifesting as HIV-associated wasting syndrome.

This systemic metabolic and nutritional complication disproportionately affects skeletal muscle and lean body mass, and it is classically defined in advanced disease by an unintentional loss of more than 10 percent of baseline body weight, frequently accompanied by chronic diarrhea, persistent weakness, or fever.

Pathophysiologically, the condition is driven by sustained immune activation and elevated pro-inflammatory cytokines, marked hypermetabolism, anorexia, and gastrointestinal malabsorption, leading to profound protein catabolism that increases overall morbidity and mortality.

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