Bulk Laxatives

Bulk laxatives, also designated as bulk-forming laxatives, are a established therapeutic class of gastrointestinal agents composed of soluble or insoluble dietary fibers and hydrophilic polymers, such as psyllium, methylcellulose, and calcium polycarbophil

Bulk laxatives, also designated as bulk-forming laxatives, are a established therapeutic class of gastrointestinal agents composed of soluble or insoluble dietary fibers and hydrophilic polymers, such as psyllium, methylcellulose, and calcium polycarbophil They exert their principal therapeutic effect by absorbing fluid within the intestinal lumen, which increases fecal mass and softens stool consistency, thereby mechanically distending the colon wall to stimulate natural peristalsis and facilit...

They exert their principal therapeutic effect by absorbing fluid within the intestinal lumen, which increases fecal mass and softens stool consistency, thereby mechanically distending the colon wall to stimulate natural peristalsis and facilitate bowel evacuation

Clinically, they serve as a first-line pharmacologic intervention for the prevention and management of simple or chronic constipation, irritable bowel syndrome with constipation (IBS-C), and conditions where straining must be minimized, such as diverticular disease, hemorrhoids, and anal fissures

Clinically, they serve as a first-line pharmacologic intervention for the prevention and management of simple or chronic constipation, irritable bowel syndrome with constipation (IBS-C), and conditions where straining must be minimized, such as diverticular disease, hemorrhoids, and anal fissures