Drug class
Intrarectal Steroids
Intrarectal steroids are a route-specific therapeutic class of topical corticosteroid medications—including formulations such as rectal foams, enemas, and suppositories of agents like hydrocortisone or budesonide—designed for targeted administration into the lower gastrointestinal tract. Read more about Intrarectal Steroids
13 drugs in this class 9 manufacturers
Drugs in Intrarectal Steroids
BUDESONIDE
HYDROCORTISONE
UCERIS (budesonide)
Intrarectal steroids are a route-specific therapeutic class of topical corticosteroid medications—including formulations such as rectal foams, enemas, and suppositories of agents like hydrocortisone or budesonide—designed for targeted administration into the lower gastrointestinal tract.
They function by activating intracellular glucocorticoid receptors, thereby suppressing local cytokine synthesis, cellular extravasation, and mucosal inflammation while substantially minimizing the systemic adverse effects seen with oral or parenteral corticosteroids.
Clinically, these agents are primarily indicated for inducing remission and controlling acute disease flares in distal inflammatory bowel diseases, notably ulcerative proctitis and left-sided ulcerative colitis.
-
fda.gov
Intrarectal steroids are a route-specific therapeutic class of topical corticosteroid medications—including formulations such as rectal foams, enemas, and suppositories of agents like hydrocortisone or budesonide—designed for targeted administration into the lower gastrointestinal tract
-
nih.gov
Intrarectal steroids are a route-specific therapeutic class of topical corticosteroid medications—including formulations such as rectal foams, enemas, and suppositories of agents like hydrocortisone or budesonide—designed for targeted administration into the lower gastrointestinal tract Clinically, these agents are primarily indicated for inducing remission and controlling acute disease flares in distal inflammatory bowel diseases, notably ulcerative proctitis and left-sided ulcerative colitis
-
nih.gov
Intrarectal steroids are a route-specific therapeutic class of topical corticosteroid medications—including formulations such as rectal foams, enemas, and suppositories of agents like hydrocortisone or budesonide—designed for targeted administration into the lower gastrointestinal tract They function by activating intracellular glucocorticoid receptors, thereby suppressing local cytokine synthesis, cellular extravasation, and mucosal inflammation while substantially minimizing the systemic adver...
-
nih.gov
Clinically, these agents are primarily indicated for inducing remission and controlling acute disease flares in distal inflammatory bowel diseases, notably ulcerative proctitis and left-sided ulcerative colitis
Sign in to follow this class
Following a drug class requires a free Physicians Office Resource account.