ALVIMOPAN
OPIOID ANTAGONISTS · POSTOPERATIVE ILEUS
Hikma Pharmaceuticals USA
Drug class
Opioid Antagonists, Peripherally-Acting
Peripherally-acting opioid antagonists—frequently designated as peripherally acting mu-opioid receptor antagonists (PAMORAs)—are a class of therapeutic agents designed to selectively inhibit opioid receptors in peripheral tissues, particularly within the gastrointestinal tract, with minimal to no penetration across the blood-brain barrier. Read more about Opioid Antagonists, Peripherally-Acting
11 drugs in this class 9 manufacturers
Drugs in Opioid Antagonists, Peripherally-Acting
RELISTOR (methylnaltrexone bromide)
OPIOID ANTAGONISTS · OPIOID-INDUCED CONSTIPATION
SALIX/BAUSCH HE
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Peripherally-acting opioid antagonists—frequently designated as peripherally acting mu-opioid receptor antagonists (PAMORAs)—are a class of therapeutic agents designed to selectively inhibit opioid receptors in peripheral tissues, particularly within the gastrointestinal tract, with minimal to no penetration across the blood-brain barrier.
By blocking local opioid binding without counteracting opioid-mediated central analgesia or precipitating central withdrawal, they restore gastrointestinal motility and secretion.
The class is primarily used to treat opioid-induced constipation in adult patients with chronic non-cancer or advanced illness pain, as well as to accelerate the recovery of gastrointestinal function following bowel resection surgery.
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fda.gov
Peripherally-acting opioid antagonists—frequently designated as peripherally acting mu-opioid receptor antagonists (PAMORAs)—are a class of therapeutic agents designed to selectively inhibit opioid receptors in peripheral tissues, particularly within the gastrointestinal tract, with minimal to no penetration across the blood-brain barrier The class is primarily used to treat opioid-induced constipation in adult patients with chronic non-cancer or advanced illness pain, as well as to accelerate t...
-
fda.gov
Peripherally-acting opioid antagonists—frequently designated as peripherally acting mu-opioid receptor antagonists (PAMORAs)—are a class of therapeutic agents designed to selectively inhibit opioid receptors in peripheral tissues, particularly within the gastrointestinal tract, with minimal to no penetration across the blood-brain barrier The class is primarily used to treat opioid-induced constipation in adult patients with chronic non-cancer or advanced illness pain, as well as to accelerate t...
-
nih.gov
Peripherally-acting opioid antagonists—frequently designated as peripherally acting mu-opioid receptor antagonists (PAMORAs)—are a class of therapeutic agents designed to selectively inhibit opioid receptors in peripheral tissues, particularly within the gastrointestinal tract, with minimal to no penetration across the blood-brain barrier By blocking local opioid binding without counteracting opioid-mediated central analgesia or precipitating central withdrawal, they restore gastrointestinal mot...
-
nih.gov
Peripherally-acting opioid antagonists—frequently designated as peripherally acting mu-opioid receptor antagonists (PAMORAs)—are a class of therapeutic agents designed to selectively inhibit opioid receptors in peripheral tissues, particularly within the gastrointestinal tract, with minimal to no penetration across the blood-brain barrier By blocking local opioid binding without counteracting opioid-mediated central analgesia or precipitating central withdrawal, they restore gastrointestinal mot...
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drugs.com
The class is primarily used to treat opioid-induced constipation in adult patients with chronic non-cancer or advanced illness pain, as well as to accelerate the recovery of gastrointestinal function following bowel resection surgery
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