AZACITIDINE
PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME ·+2
BLUEPOINT/ONCOP
Drug class
Pyrimidine Analogs
Pyrimidine analogs are a subclass of antimetabolite drugs structurally designed to mimic endogenous pyrimidines such as uracil, thymine, and cytosine. Read more about Pyrimidine Analogs
100 drugs in this class 55 manufacturers
Drugs in Pyrimidine Analogs
CAPECITABINE
5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
BLUEPOINT/ONCOP
FLUOROURACIL
5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
XIROMED, LLC
DECITABINE
PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME
NOVADOZ-NOVAPLU
AZACITIDINE
PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME ·+2
MEITHEAL-NOVAPL
AZACITIDINE
PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME ·+2
Hikma Pharmaceuticals USA
DECITABINE
PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME
Hikma Pharmaceuticals USA
DECITABINE
PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME
FRESENIUS KABI
FLUOROURACIL
5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
FRESENIUS KABI
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Pyrimidine analogs are a subclass of antimetabolite drugs structurally designed to mimic endogenous pyrimidines such as uracil, thymine, and cytosine.
By inhibiting essential nucleic acid synthetic enzymes—such as thymidylate synthase or DNA polymerase—or by directly incorporating into DNA and RNA to cause strand breaks and chain termination, these agents disrupt cell division and trigger apoptosis in rapidly dividing cells.
The class plays a fundamental therapeutic role in oncology, serving as frontline and maintenance treatments for hematologic malignancies and various solid tumors, including colorectal, breast, pancreatic, and gastric cancers.
Select pyrimidine-derived agents are also employed clinically to manage severe viral and fungal infections.
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nih.gov
Pyrimidine analogs are a subclass of antimetabolite drugs structurally designed to mimic endogenous pyrimidines such as uracil, thymine, and cytosine By inhibiting essential nucleic acid synthetic enzymes—such as thymidylate synthase or DNA polymerase—or by directly incorporating into DNA and RNA to cause strand breaks and chain termination, these agents disrupt cell division and trigger apoptosis in rapidly dividing cells The class plays a fundamental therapeutic role in oncology, serving as fr...
-
nih.gov
Pyrimidine analogs are a subclass of antimetabolite drugs structurally designed to mimic endogenous pyrimidines such as uracil, thymine, and cytosine By inhibiting essential nucleic acid synthetic enzymes—such as thymidylate synthase or DNA polymerase—or by directly incorporating into DNA and RNA to cause strand breaks and chain termination, these agents disrupt cell division and trigger apoptosis in rapidly dividing cells
-
cancer.gov
By inhibiting essential nucleic acid synthetic enzymes—such as thymidylate synthase or DNA polymerase—or by directly incorporating into DNA and RNA to cause strand breaks and chain termination, these agents disrupt cell division and trigger apoptosis in rapidly dividing cells The class plays a fundamental therapeutic role in oncology, serving as frontline and maintenance treatments for hematologic malignancies and various solid tumors, including colorectal, breast, pancreatic, and gastric cancer...
-
fda.gov
The class plays a fundamental therapeutic role in oncology, serving as frontline and maintenance treatments for hematologic malignancies and various solid tumors, including colorectal, breast, pancreatic, and gastric cancers
-
cancer.gov
The class plays a fundamental therapeutic role in oncology, serving as frontline and maintenance treatments for hematologic malignancies and various solid tumors, including colorectal, breast, pancreatic, and gastric cancers
-
nih.gov
Select pyrimidine-derived agents are also employed clinically to manage severe viral and fungal infections
-
nih.gov
Select pyrimidine-derived agents are also employed clinically to manage severe viral and fungal infections
-
nih.gov
Select pyrimidine-derived agents are also employed clinically to manage severe viral and fungal infections
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