Drug class

Pyrimidine Analogs

Pyrimidine analogs are a subclass of antimetabolite drugs structurally designed to mimic endogenous pyrimidines such as uracil, thymine, and cytosine. Read more about Pyrimidine Analogs

100 drugs in this class 55 manufacturers

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Drugs in Pyrimidine Analogs

Showing 64–72 of 100 drugs

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
AREVA PHARMACEU

AZACITIDINE

PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME ·+2
APOTEX CORP

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
ALEMBIC PHARMAC

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
AHP

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
SUN PHARMACEUTI

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
LIFESTAR PHARMA

DECITABINE

PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME
ATHENEX PHARMAC

GEMCITABINE HCL

PYRIMIDINE ANALOGS · METASTATIC BREAST CARCINOMA ·+5
ATHENEX PHARMAC

AZACITIDINE

PYRIMIDINE ANALOGS · MYELODYSPLASTIC SYNDROME ·+2
MEITHEAL PHARMA
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About Pyrimidine Analogs.

Pyrimidine analogs are a subclass of antimetabolite drugs structurally designed to mimic endogenous pyrimidines such as uracil, thymine, and cytosine.

By inhibiting essential nucleic acid synthetic enzymes—such as thymidylate synthase or DNA polymerase—or by directly incorporating into DNA and RNA to cause strand breaks and chain termination, these agents disrupt cell division and trigger apoptosis in rapidly dividing cells.

The class plays a fundamental therapeutic role in oncology, serving as frontline and maintenance treatments for hematologic malignancies and various solid tumors, including colorectal, breast, pancreatic, and gastric cancers.

Select pyrimidine-derived agents are also employed clinically to manage severe viral and fungal infections.