AKYNZEO (netupitant/palonosetron HCl)
ANTIEMETIC · PREVENTION OF CANCER CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING
HELSINN THERAPE
Drug class
Selective Serotonin 5-HT3 Antagonists
Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone. Read more about Selective Serotonin 5-HT3 Antagonists
115 drugs in this class 80 manufacturers
Drugs in Selective Serotonin 5-HT3 Antagonists
ONDANSETRON HCL
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
Hospira
ONDANSETRON HCL (ondansetron HCl/PF)
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
Hospira
ONDANSETRON HCL
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2
Actavis Pharma
ONDANSETRON HCL (ondansetron HCl/PF)
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
FRESENIUS KABI
ONDANSETRON HCL
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
CLARIS/BAXTER
PALONOSETRON HCL
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
DR.REDDY'S LAB
PALONOSETRON HCL
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
SANDOZ
PALONOSETRON HCL
ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
FRESENIUS KABI
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Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone.
By blocking serotonin-mediated emetic signaling, these agents primarily serve as potent antiemetics to prevent and manage nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgical procedures.
Additionally, specific agents in this class are utilized in gastroenterology to treat severe diarrhea-predominant irritable bowel syndrome by reducing colonic motility and visceral sensitivity.
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nih.gov
Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone By blocking serotonin-mediated emetic signaling, these agents primarily serve as potent antiemetics to prevent and manage nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgical procedures
-
nih.gov
By blocking serotonin-mediated emetic signaling, these agents primarily serve as potent antiemetics to prevent and manage nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgical procedures
-
fda.gov
Additionally, specific agents in this class are utilized in gastroenterology to treat severe diarrhea-predominant irritable bowel syndrome by reducing colonic motility and visceral sensitivity
-
nih.gov
Additionally, specific agents in this class are utilized in gastroenterology to treat severe diarrhea-predominant irritable bowel syndrome by reducing colonic motility and visceral sensitivity
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