Drug class

Selective Serotonin 5-HT3 Antagonists

Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone. Read more about Selective Serotonin 5-HT3 Antagonists

115 drugs in this class 80 manufacturers

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Drugs in Selective Serotonin 5-HT3 Antagonists

Showing 55–63 of 115 drugs

SANCUSO (granisetron)

ANTIEMETIC · PREVENTION OF CANCER CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING
KYOWA/CUMBERLAN

PALONOSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1
Baxter Healthcare Company

ONDANSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2
BLENHEIM PHARMA

ONDANSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2
ATLANTIC BIOLOG

ONDANSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2
AVPAK

ONDANSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2
A-S MEDICATION
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About Selective Serotonin 5-HT3 Antagonists.

Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone.

By blocking serotonin-mediated emetic signaling, these agents primarily serve as potent antiemetics to prevent and manage nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgical procedures.

Additionally, specific agents in this class are utilized in gastroenterology to treat severe diarrhea-predominant irritable bowel syndrome by reducing colonic motility and visceral sensitivity.