Drug class

Surfactant Laxatives

Surfactant laxatives, commonly referred to as stool softeners, are a class of gastrointestinal agents that include compounds such as docusate salts. Read more about Surfactant Laxatives

184 drugs in this class 73 manufacturers

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Drugs in Surfactant Laxatives

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About Surfactant Laxatives.

Surfactant laxatives, commonly referred to as stool softeners, are a class of gastrointestinal agents that include compounds such as docusate salts.

They function primarily as anionic detergents that lower the surface tension at the oil-water interface within the intestinal lumen, thereby facilitating the penetration of water and lipids into the fecal mass to soften hard stools and ease transit.

Clinically, these agents are primarily indicated for the prevention and management of mild constipation and to minimize physical straining during defecation.

They are especially favored in clinical scenarios where straining must be avoided, such as following myocardial infarction, abdominal surgery, or in patients with painful anorectal conditions like hemorrhoids and anal fissures.