GLEEVEC (imatinib mesylate)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
Novartis Pharmaceuticals
Indication
Unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor
An unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor is an advanced mesenchymal malignancy of the digestive tract arising from the interstitial cells of Cajal or their precursors. Read more about Unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor
28 drugs 27 manufacturers
Drugs that treat it
Common Unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor therapies.
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
SUN PHARMA GLOB
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
APOTEX CORP
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
TEVA USA
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
Mylan Pharmaceuticals
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
MYLAN INSTITUTI
IMATINIB MESYLATE
PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
NORTHSTAR RX LL
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
Major Pharamceuticals
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA·+11
DR.REDDY'S LAB
Filter & compare in the drug finder →Opens the drug finder with Unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor preselected.
News & literature
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Coming soonAn unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor is an advanced mesenchymal malignancy of the digestive tract arising from the interstitial cells of Cajal or their precursors.
Pathophysiologically, the tumor is characterized by strong immunohistochemical expression of the CD117 cell-surface marker, which corresponds to the KIT receptor tyrosine kinase and is predominantly driven by activating mutations that stimulate unchecked cellular proliferation.
In this clinical state, the neoplasm has either grown to involve critical structures making complete surgical removal impossible (unresectable) or has disseminated to distant sites, most commonly the liver and peritoneum (metastatic).
Affected adult populations often present with abdominal masses, gastrointestinal bleeding, obstruction, or systemic symptoms associated with advanced abdominal malignancy.
- nih.gov
An unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor is an advanced mesenchymal malignancy of the digestive tract arising from the interstitial cells of Cajal or their precursors Pathophysiologically, the tumor is characterized by strong immunohistochemical expression of the CD117 cell-surface marker, which corresponds to the KIT receptor tyrosine kinase and is predominantly driven by activating mutations that stimulate unchecked cellular proliferation In this clinic...
- nih.gov
An unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor is an advanced mesenchymal malignancy of the digestive tract arising from the interstitial cells of Cajal or their precursors Pathophysiologically, the tumor is characterized by strong immunohistochemical expression of the CD117 cell-surface marker, which corresponds to the KIT receptor tyrosine kinase and is predominantly driven by activating mutations that stimulate unchecked cellular proliferation
- mdanderson.org
An unresectable or metastatic Kit (CD117) positive gastrointestinal stromal tumor is an advanced mesenchymal malignancy of the digestive tract arising from the interstitial cells of Cajal or their precursors In this clinical state, the neoplasm has either grown to involve critical structures making complete surgical removal impossible (unresectable) or has disseminated to distant sites, most commonly the liver and peritoneum (metastatic)
- nih.gov
Pathophysiologically, the tumor is characterized by strong immunohistochemical expression of the CD117 cell-surface marker, which corresponds to the KIT receptor tyrosine kinase and is predominantly driven by activating mutations that stimulate unchecked cellular proliferation Affected adult populations often present with abdominal masses, gastrointestinal bleeding, obstruction, or systemic symptoms associated with advanced abdominal malignancy
- dana-farber.org
In this clinical state, the neoplasm has either grown to involve critical structures making complete surgical removal impossible (unresectable) or has disseminated to distant sites, most commonly the liver and peritoneum (metastatic)
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